ABSTRACT
Objective To explore the infection rate,the correlated risk factors and knowledge of Helicobacter Pylori infection among the outpatients with 13C-urea breath test (13C-UBT).Methods 13C-UBT was performed to evaluate the HP infection status.Self-designed questionnaires were adopted to conduct investigation among 500 outpatients with 13C-UBT and then the results were analyzed.Results The HP infection rate was 46％ in our research.Demographic factors of ages in different groups,on the job or not,HP testing times and different education degree as well as having susceptible factors of family history of HP infection or not,using the public chopsticks or not,sitting up late,history of digestive disease were statistically significant.Positive HP infection was statistically significant different in people with different knowledge of HP infection.71.8％ of the patients had never heard of the HP could cause none digestive system diseases,61.4％ of the patients didn't know how to use drug combination,64.6％ of patients didn't know the review time and 53.4％ of patients did not know how to prevent and control HP infection.Conclusions There is high HP infection rate in outpatients receiving 13C-UBT.The infectious sources of HP commonly exist in population,and the route of transmission was various.We should focus on the susceptible people and strengthen health education,advocate eating separately,improve sanitary consciousness,add HP-test in the health test and enhance the reasonable intervention about HP infection.
ABSTRACT
AIM: To investigate the role of catecholamine, angiotensin converting enzyme(ACE) and adenosine triphosphatase in ischemic preconditioning in isolated rat hearts. METHODS: Isolated perfused rat heart was subjected to global ischemia for 40 min followed by reperfusion for 10 min (I/R). Preconditioning (PC) was induced by 5 min of ischemia and 10 min of reperfusion. The tissue concentrations in NE, and ACE, ATPase activities were determined in left ventricle in the PC and I/R groups by fluorometry and spectrophotometry. RESULTS: There were no significant difference in NE and ACE between PC and I/R groups. PC hearts showed improved recovery of the contractile function after 40 min ischemia/10 min reperfusion, but activities of the myocardial total ATPase, Mg2＋-ATPase, Na＋K＋-ATPase were inhibited markedly compared with I/R group. CONCLUSION: The inhibited myocardial ATPase may be involved in the mechanism of ischemic preconditioning protection in the isolated rat heart. Endogenous myocardial norepinephrine and ACE activation are not essential for ischemic preconditioning in the isolated rat heart.